The Bulletin

Applicant:

Victoria University of Wellington

Application Code:

GMD08080

Purpose:

To develop in containment non-pathogenic strains of Escherichia coli modified with native marine pulmonate mollusc DNA in order to isolate genetic markers for use in taxonomic, population and evolutionary studies

Date Formally Received:

4 March2009

Applicant:

University of Otago

Application Code:

GMD08011

Purpose:

To determine the functions of viral and cellular proteins on cellular pathways, tissue physiology and tissue immunology, by delivering genes to animal cells and whole animals

Date Formally Received:

12 March 2009

Applicant:

Wellington Zoo Trust

Application Code:

NOC08010

Purpose:

To import into containment 28 mammal species for captive breeding, display, educational presentations and to contribute to conservation by exposing visitors to conservation issues and the conservation of genetic material through breeding

Decision Notified:

16 March 2009

Description of Organisms:

Tachyglossus aculeatus Shaw, 1792
Phascolarctos cinereus Goldfuss, 1817
Sarcophilus harrisii Boitard, 1841
Lasiorhinus latifrons Owens, 1845
Acrobates pygmaeus Shaw, 1793
Potorous tridactylus Kerr, 1792
Macropus fuliginosus Desmarest, 1871
Galago moholi A. Smith, 1836
Galago senegalensis É. Geoffroy Saint-Hilaire, 1796
Otolemur crassicaudatus É. Geoffroy Saint-Hilaire, 1812
Otolemur garnettii Ogilby, 1838
Saimiri boliviensis I. Geoffroy Saint-Hilaire and Blainville, 1834
Mandrillus sphinx Linnaeus, 1758
Trachypithecus francoisi Pousargues, 1898
Colobus guereza Rüppell, 1835
Gorilla gorilla Savage and Wyman, 1847
Ursus arctos Linnaeus, 1758
Crocuta crocuta Erxleben, 1777
Felis margarita Loche, 1858
Felis nigripes Burchell, 1824
Caracal caracal Schreber, 1776
Leopardus pardalis Linnaeus, 1758
Leopardus wiedii Schinz, 1821
Neofelis nebulosa Griffith, 1821
Uncia uncia Schreber, 1775
Diceros bicornis Linnaeus, 1758
Hexaprotodon liberiensis Morton, 1849
Tragulus javanicus Osbeck, 1765

Decision:

Approved with Controls

ERMA Approval Code:

NOC002541-568

Applicant:

Landcare Research New Zealand Limited

Application Code:

NOC09001

Purpose:

To assess the insects, Bhadorcosma lonicerae, Apha aequalis, Limenitis camilla, Limenitis glorifica, Oberea mixta and Zaraea lewisii as potential biological control agents for the weed Japanese honeysuckle (Lonicera japonica) in New Zealand

Decision Notified:

30 March 2009

Description of Organisms:

Apha aequalis (Felder, 1874)
Bhadorcosma lonicerae (Moriuti, 1977)
Limenitis Camilla (Linnaeus, 1764)
Limenitis glorifica (Fruhstorfer, 1909)
Zaraea lewisii (Cameron,1886)
Oberea mixta (Bates 1873)

Decision:

Approved with Controls

ERMA Approval Code:

NOC002569 - 74

Applicant:

AgResearch Limited

Application Code:

GMC09001

Purpose:

Ovine muscle cells with modifications to promote cellular proliferation, for the study of muscle growth and stem cell commitment

Decision Notified:

18 March 2009

Host Organisms to be modified:

Ovis aries (Linnaeus, 1758) cell line

Decision:

Approved with Controls

ERMA Approval Code:

GMC001389

BCH Number:

48409

Applicant:

Victoria University of Wellington

Application Code:

GMD08080

Purpose:

To develop in containment non-pathogenic strains of Escherichia coli modified with native marine pulmonate mollusc DNA in order to isolate genetic markers for use in taxonomic, population and evolutionary studies

Decision Notified:

5 March 2009

Host Organisms to be modified:

Escherichia coli (Migula 1895) Castellani and Chalmers 1919 non pathogenic laboratory strains
Bacteriophage lambda (ICTV approved name is Enterobacteria phage λ), non pathogenic laboratory strains

Decision:

Approved with Controls

ERMA Approval Code:

GMD005315-16

BCH Number:

48317-18

Applicant:

Lincoln University

Institute Code:

GMO08/LU003

Application Code:

GMD09020

Purpose:

To develop genetically modified strains of Erwinia and Escherichia coli for genetic characterisation of pectolytic Erwinia causing soft rot diseases of crops and the virulence factors involved in their colonisation of plant hosts

Decision Notified:

25 March 2009

Host Organisms to be modified:

Erwinia carotovorum (Jones 1901) synonym: Pectobacterium carotovorum
Erwinia chrysanthemi (Burkholder et al. 1953) synonym: Dickeya chrysanthemi synonym: Pectobacterium  chrysanthemi
Escherichia coli (Migula 1895) Castellani & Chalmers 1919
(attenuated laboratory strains such as B and K12 and derivatives)

Decision:

Approved with Controls

ERMA Approval Code:

GMD005334 - 36

BCH Number:

48445 - 47

Applicant:

Lincoln University

Institute Code:

GMO08/LU004

Application Code:

GMC09002

Purpose:

To import bacteriophage genetic libraries containing genes derived from thornfish and black cod (Bovichtus variegatus, Notothenia angustata, respectively) in order to study environmental adaptations, particularly to extreme environments

Decision Notified:

10 March 2009

Host Organisms to be modified:

Bacteriophage lambda

Decision:

Approved with Controls

ERMA Approval Code:

GMC001388

BCH Number:

48377

Applicant:

Lincoln University

Institute Code:

GMO08/LU005

Application Code:

GMD09013

Purpose:

To develop fish and invertebrate genetic resources for sequencing, phylogenetic and functional expression studies through cloning of genes into Escherichia coli and genomic and cDNA library construction using standard laboratory λ-phage or plasmid vectors

Decision Notified:

10 March 2009

Host Organisms to be modified:

Bacteriophage lambda (ICTV approved name is Enterobacteria phage λ)
Escherichia coli (Migula 1895) Castellani & Chalmers 1919

Decision:

Approved with Controls

ERMA Approval Code:

GMD005317 - 18

BCH Number:

48378 - 79

Applicant:

University of Auckland

Institute Code:

GMO09/UA003

Application Code:

GMD09019

Purpose:

The use of low risk genetic modification to study ciliary function

Decision Notified:

24 March 2009

Host Organisms to be modified:

Canis familiaris (Linnaeus, 1758) (cell lines)
Chlorocebus aethiops (Linnaeus,1758) (cell lines)
Cricetulus griseus (Milne Edwards,1857) (cell lines)
Cricetus cricetus (Linnaeus,1758) (cell lines)
Escherichia coli (Migula 1895) Castellani & Chalmers 1919
(non pathogenic laboratory adapted strains)
Homo sapiens (Linnaeus, 1758) (cell lines)
Mesocricetus auratus (Waterhouse,1839) (cell lines)
Mus musculus Linnaeus, 1758 (established and primary cell lines)
Mus spretus (Latase,1883) (established and primary cell lines)
Rattus norvegicus (Berkenhout, 1769) (established and primary cell lines)
Rattus rattus (Linnaeus, 1758) (established and primary cell lines)

Decision:

Approved with Controls

ERMA Approval Code:

GMD005323 - 33

BCH Number:

48420 - 30

Applicant:

University of Otago

Institute Code:

GMO08/UO021

Application Code:

GMD09014

Purpose:

Development of stably transformed cell lines that express fluorescent proteins in order to fully assess metastasis in a mouse xenograft model of (ER-negative) breast cancer

Decision Notified:

11 March 2009

Host Organisms to be modified:

Escherichia coli (Migula 1895) Castellani & Chalmers 1919
(attenuated laboratory strains such as B and K12 and derivatives)
Homo sapiens (Linnaeus, 1758) (commercially available human cancer cell lines)

Decision:

Approved with Controls

ERMA Approval Code:

GMD005319 - 20

BCH Number:

48380 - 81

Applicant:

University of Otago

Institute Code:

GMO08/UO022

Application Code:

GMC09004

Purpose:

To import vaccinia viruses (VACVs) which have been modified by deletion of sequences within genes involved in viral DNA replication such as ribonucleotide reductase subunits and thymidine kinase in order to examine the function of orf virus genes

Decision Notified:

25 March 2009

Host Organisms to be modified:

Vaccina virus strains (such as Lister and Copenhagen with mutations in genes involved in viral replication)

Decision:

Approved with Controls

ERMA Approval Code:

GMC001390

BCH Number:

48444

Applicant:

University of Otago

Institute Code:

GMO08/UO023

Application Code:

GMD09015

Purpose:

To prove that genetically modified Rhodococcus opacus can accumulate triacylglycerides intracellularly when grown on readily available nitrogen-containing substrates

Decision Notified:

11 March 2009

Host Organisms to be modified:

Escherichia coli (Migula 1895) Castellani & Chalmers 1919
(attenuated laboratory strains such as B and K12 and derivatives)
Rhodococcus opacus (Klatte et al. 1995) (such as strain PD630)

Decision:

Approved with Controls

ERMA Approval Code:

GMD005321 - 22

BCH Number:

48382 - 83

Applicant:

The New Zealand Institute for Plant and Food Research Limited (Auckland)

Application Code:

GMD00294

Purpose:

Novel binary vectors for efficient and precise petunia transformation to study the process of plant development

Decision Amendment Date:

4 March 2009

Amendment:

To add Trifolium repens to the source of approved donor DNA