Toxicity, Ecotoxicity and Chemistry Data Sources for Hazardous Substance Applications

Toxicity, ecotoxicity and chemistry data relevant to applications for hazardous substances under Part V of the HSNO Act is widely available on the internet, generally free of charge. The following links to databases are provided for applicants to assist with the preparation of applications.

Please note that this is not a complete list of potential data sources. Subject to the information requirements for the type of application to be submitted, you may need to consider searching more widely for data in support of the application. Any internet search engine may be used, with relevant key search terms.

General Information

TOXNET
  • The US National Library of Medicine's (NLM) Toxicology Data Network; access to several databases
  • ChemIDplus Chemical synonyms, structures and more
  • HSDB Hazardous Substances Databank
  • CCRIS Chemical Carcinogenesis Research Info System
  • IRIS Integrated Risk Information System
  • DART / ETIC Development and Reproductive Toxicology, and Environmental Teratology Information Center
  • GENETOX Genetic Toxicology (mutagenicity)
  • TOXLINE Toxicology bibliographic info.
EPA Factsheets  
European Chemical Bureau

Existing Chemicals and Classification, and Labelling, are useful sub-sites.

Patty's Industrial Hygiene and Toxicology

Gives general information on chemicals. Subscription required.

National Toxicology Programme (NTP)

Consists of relevant toxicology activities of the National Institutes of Health's National Institute of Environmental Health Sciences (NIH/NIEHS), the Centers for Disease Control and Prevention's National Institute for Occupational Safety and Health (CDC/NIOSH), and the Food and Drug Administration's National Center for Toxicological Research (FDA/NCTR).

ChemFinder

General information on chemicals. Individual access is complimentary on a limited basis.

GHS

Access to the Globally Harmonised System for the Classification and Labelling of Chemicals.

Pesticides

US EPA

Pesticide Reregistration Eligibility Documents (RED) on various pesticides.

ACVM

List of registered pesticides (and veterinary medicines) in New Zealand maintained by the Agricultural Compounds and Veterinary Medicines Group of the New Zealand Food Safety Authority.

APVMA

Australian Regulatory Agency for assessment of Pesticide/Veterinary Medicines.

Toxicity

IPCS INCHEM

Access to the International Programme for Chemical Safety documents on pesticides and veterinary medicines (JECFA and JMPR), IARC summaries (International Agency for Research on Cancer).

European Union On-line

European Union new active substance evaluations.

European Union On-line

Access to the European Union existing active substance evaluations.

European Medicines Agency

Access to the European Agency for the Evaluation of Medicinal Products (EMEA) - veterinary and human medicines.

IARC - International Agency for Research on Cancer

Monographs on the evaluation of carcinogenic risk to humans, and other resources.

NICNAS

Australian NICNAS chemical assessment reports.

Ecotoxicity

USEPA ECOTOX

Access to the EPA's ECOTOX database.

National Chemicals Inspectorate, Sweden

Access to the N-class database for ecotoxic classifications.